13^th International Conference on COPD and Lung Health November 28-29, 2024 London, UK

Chronic obstructive pulmonary (COPD) disease is that chronic airflow limitation results from an abnormal inflammatory response to inhaled particles and gases in the lung. Pathologic changes in COPD occur in the generous airways, the small bronchioles, and the lung parenchyma. The pathogenic mechanisms are not clear but are most likely diverse. Increased number of activated polymorph nuclear leukocytes and macrophages release elastases in a manner that cannot be counteracted effectively by antiproteases, emerge in lung desolation

• Chronic bronchitis
• Emphysema
• Refractory asthma

Emphysema is a progressive and chronic lung disease that falls under the broader category of Chronic Obstructive Pulmonary Disease (COPD). It is characterized by the destruction of the air sacs (alveoli) in the lungs, leading to a loss of their elasticity. This loss of elasticity reduces the ability of the lungs to expand and contract efficiently, impairing normal airflow. Regular follow-ups with healthcare professionals are essential for monitoring the progression of the disease and adjusting the treatment plan accordingly.

•  Alveolar Damage
• Shortness of Breath
•  Chronic Cough
•  Wheezing

Spirometry is a diagnostic test measuring lung function by assessing the volume and flow of inhaled and exhaled air. This non-invasive procedure aids in diagnosing respiratory conditions such as asthma, chronic obstructive pulmonary disease (COPD), and pulmonary fibrosis. During spirometry, a person inhales deeply and then exhales forcefully into a device called a spirometer. The results, including vital capacity and forced expiratory volume, help evaluate lung health, identify abnormalities, and guide treatment decisions. Spirometry is a valuable tool for monitoring respiratory diseases, assessing lung function impairment, and optimizing patient care.

Chronic bronchitis is a type of chronic obstructive pulmonary disease (COPD), which is a group of progressive lung diseases that make it difficult to breathe. It is characterised by inflammation of the bronchial tubes, which are the air passages that carry air to the lungs. This inflammation leads to increased production of mucus and other changes in the bronchial tubes. Chronic bronchitis can significantly impact daily life and, if not managed, may contribute to the progression of COPD.

•  Acute Bronchitis
•  Allergic Bronchitis
•  Reactive Airway Disease (RAD)
• Inflammation and Mucus Production

Tobacco control is a critical aspect of managing chronic obstructive pulmonary disease (COPD) because cigarette smoking is the leading cause of COPD. COPD encompasses conditions such as chronic bronchitis and emphysema, characterized by progressive airflow limitation and difficulty breathing. Controlling tobacco use is central to preventing and managing COPD. Multifaceted approaches that combine public health policies, clinical interventions, and community engagement are crucial for reducing the burden of COPD associated with tobacco smoking.

• Smoking Cessation
• Tobacco Control Policies
• Integrated Care
• Public Awareness Campaigns

Pulmonary Rehabilitation is a program designed for people with chronic breathing conditions that limit the quality of life and to increase awareness about chronic lung disease. And also learn to achieve exercise with less shortness of breath. Physiologists and respiratory therapists help to determine a safe exercise routine and learn how to exercise. The program teaches a person to be in charge of breathing instead of breathing being the in charge of person. Pulmonary rehabilitation staff will supervise the exercise sessions. And the amount of time taken by the patient for exercise will be increased in gradually, therefore the level of difficulty will change based on your ability. As the muscles get stronger, the patient will exercise longer with less breathlessness.

• Exercise training
• Nutritional counselling
• Energy-conserving techniques
• Breathing strategies
• Psychological counselling

Lung cancer is a malignancy that originates in the lung cells, typically caused by tobacco smoke. It is broadly classified into non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). Symptoms include persistent cough, chest pain, and shortness of breath. Diagnosis involves imaging tests and biopsies, with treatment options such as surgery, radiation, Chemotherapy, targeted therapy, and immunotherapy. Prevention includes smoking cessation and minimizing exposure to carcinogens. Ongoing research aims to enhance early detection and develop more effective treatments.

People with different kinds of COPD experience difficulty in breathing and shortness of breath. The two major infections that fall under the extent of COPD are: Chronic bronchitis, which involves a long-term cough with mucus, it is a long-term inflammation of the bronchi, which results in increased exhibition of mucus, as well as other changes. These changes may result in breathing problems, frequent infections, cough, disability, anxiety and depression. Emphysema which includes harms to the lungs over time. Emphysema is a chronic lung condition in which alveoli may be destroyed, narrowed, narrowed, stretched, and over-inflated. This can cause a reduction in respiratory volume and breathlessness. Harm to the air sacs is irreversible and brings about permanent "holes" in the lung tissue

Chronic obstructive pulmonary disease is an expanding worldwide medical issue and cause of death. COPD mostly influencing small airway routes and lung parenchyma that prompts dynamic aviation route deterrent. COPD is a standout amongst the most widely recognized infections on the globe, and there is a global increase in generality, however there are no drugs available at present that halt the relentless progression of this disease. In any case, a superior perception of the cell and molecular mechanisms that are associated with the underlying inflammatory and destructive processes has uncovered a few new centres for which drugs are presently being developed, and the prospects for detection new medications are good.

COVID-19 is a respiratory disease which causes a range of breathing issues, from mild to critical. Older adults and people who have other health conditions like heart disease, cancer and diabetes may have more significant symptoms when compared to others. Coronavirus can infect the upper or lower part of the respiratory zone and travels down the airways making the edge become irritated and inflamed. In some instances, the infection can reach all the way down into the alveoli. Respiratory inflammation can be notice on a chest X-ray or CT scan. Contemporary, convalescent plasma from a recovered patient is given by transfusion to a patient who is suffering from COVID-19. The donor antibodies may help the patient fight the illness, possibly shortening the reducing the severity of the disease

The major test for diagnosing COPD is a lung function test is known as spirometer which involves the use of a machine called a spirometer that measures how much air you are able to move by taking a deep breathe in and out, and how rapidly you are able to do so. Arterial blood gas analysis is second important test in diagnosing COPD. This test measures how much oxygen and carbon dioxide are present in the blood. A high percentage of carbon dioxide in the blood can be an indication of badly functioning lungs.

The principal methods of treatment are pharmacotherapy and smoking cessation, while pulmonary rehabilitation, long-term oxygen therapy, and surgery may be considered in selected patients. Steroids, inhalers and antibiotics may be prescribed to treat various indications of COPD. Smoking stoppage is the most effective interference in stopping the progression of COPD, as well as increasing survival rate of persons suffering with COPD. Hence, smoking stoppage should be the main priority in the treatment of COPD

A lung transplant is a surgical procedure to replace a diseased lung with a healthy lung. It is used to improve the quality of life and prolong the lifespan in people affected with severe or advanced chronic lung cases. The surgery can be for one lung or for both. Lung transplants can be over on people of almost all ages from new born to adults up to age 65.

There is no formal organizing system for pulmonary fibrosis. Physicians use different factors, like the ones listed below to describe the disease as mild, moderate, severe or very severe.

Symptoms:

• Pulmonary Function Test or Lung function Test
• Six minute walk test
• A high resolution CT scan

Lung cancer is a condition that causes cells to divide in the lungs uncontrollably which leads to the growth of tumours that reduce a person's ability to breathe. Symptoms of lung cancer involves appetite loss, changes to a person's voice, such as hoarseness, regular chest infections, such as bronchitis or pneumonia, lingering cough that may start to get worse, shortness of breath, unexplained headaches, weight loss and wheezing.

Early diagnosis of lung cancer: It can be lifesaving because lung cancer cells can travel to other parts of the body before a doctor detects them in the lungs. If metastasis has taken place, it makes treating the disease much more difficult.

Treatment for lung cancer: It is based on its location and stage, as well as the overall health of the individual. Possible treatments include

• Surgery
• Chemotherapy
• Radiation therapy and targeted therapy

Chronic Obstructive Pulmonary Disease (COPD) and Asthma are especially vulnerable to the obviously harmful effects of air pollutants. Air pollution can cause the increase of COPD and onset of asthma, increase the respiratory morbidity and mortality.

Air pollutants such as materials from the fuel combustion can cause inflammation in lungs and further impaired the decreased pulmonary function in COPD patients.

People especially those with COPD or asthma should be aware of the air quality and take excess measures.

Cardio Pulmonary Disorders are illustrating as the range of serious disorders that affects the heart and lungs. Cardiovascular disease is represent as any abnormal condition characterised heart or blood vessel dysfunction. Cardiovascular Disease (CVD) contains diseases affecting the Heart and blood vessels.

Respiratory Failure occurs when lungs fail to do their job passing oxygen into your bloodstream and eliminate carbon dioxide. It is a complication of chronic obstructive pulmonary disease (COPD) and other severe respiratory disorders.

COPD prevents the lungs from working efficiently, which can lead to complications

Respiratory Tract Infections are any infectious diseases of the upper and lower respiratory tract.

• Upper respiratory tract infection
• Lower respiratory tract infection

• Tuberculosis (TB)

• Influenza (Flu)

Upper Respiratory Tract Infection (sinuses and throat)

The infections are caused by virus. Upper respiratory tract (which starts at sinuses and ends at vocal chords) infection includes the common cold, laryngitis, pharyngitis/tonsillitis, acute rhinitis, acute rhinosinusitis and acute otitis media.

Lower Respiratory Tract Infection (airways and lungs)

Lower respiratory system begins at vocal chords and ends at lungs. Lower respiratory tract infections includes acute bronchitis, bronchiolitis, pneumonia and tracheitis. Lower respiratory tract infections tend to establish and can be severe.

Sleep Medicine is a multidisciplinary field with contributions by practitioners and researchers from different disciplines. Pulmonary medicine has made important contributions to the field of sleep medicine for the past many years.

Patients suffering from COPD have sleep protests characterized by a longer time to fall asleep, more constant arousals and awakenings in sleep, and generalized insomnia. Sleep disturbance leads to be more severe as the disease advances and substantially reducing the patient’s quality of life.

Primary Prevention: Avoid exposure, Help fight for clean air, never start smoking or quit smoking, reduce your exposure to COPD causing irritants

Secondary Prevention: Vaccination and Physical activity

Self-Management arrangement in COPD includes quitting smoking, improving exercise and physical activity levels, proper nutrition, and medication adherence. It is concentrating on a system for the exacerbation, and enhanced communication between the patient and health care providers make good clinical sense. It is deliberated an integral components of chronic care model of disease management which involves health care organization, community resources, delivery system redesign, and clinical information systems.

It helps the patient to acquire knowledge and skills required to follow the medical therapies. An efficient review of self-management in COPD concluded that it reduces hospital admissions and has no adverse effects.

Anxiety and depression are common in patients affected by the chronic obstructive pulmonary disease (COPD). The degree of lung function might not describe anxiety and depression. These are difficult to identify and deal with their symptoms often project with those of COPD. Also, increase the risk of re-hospitalization and mortality. Dyspnea and reduced act capacity are the mechanisms that lead to the symptoms of anxiety and depression associated with COPD. Pulmonary rehabilitation develops anxiety and depression in COPD

Pediatric Pulmonology is a medical speciality that deals with the diagnosis and treatment of diseases involving respiratory tract and it is a combination of both pulmonology and paediatrics. These are specially qualified in pulmonary pediatric diseases and conditions of chest.

Pediatric pulmonology and Critical Care is accomplished to caring for critically ill patients and patients with lung diseases- asthma, pneumonia, wheezing, bronchitis, COPD, cystic fibrosis. The division of pediatric pulmonary and critical care is consisted of a team of outstanding clinicians, scientists, and scholars dedicated to improve the lives of patients with serious lung disease and those who are critically ill.

Chronic obstructive pulmonary disease is one of the leading causes of disability and death worldwide Chronic Obstructive Pulmonary Disease is a progressive disease that causes airflow blockage and problems related to breathing. It can cause coughing that produces large amounts of a slimy substance called mucus, wheezing, and shortness of breathe as well as chest tightness. Cigarette smoking is the main cause of COPD. Long-term exposure to various lung irritants such as air pollution, chemical fumes or dusts also contributes to COPD. A rare genetic situation called alpha-1 antitrypsin (AAT) deficiency can also lead to COPD. COPD cannot be cured but it can be treated to lower the chance of complications, and generally improve quality of life

Pulmonary diseases encompass a diverse range of conditions affecting the respiratory system. These diseases compromise lung function, leading to symptoms like coughing, shortness of breath, and chest pain. Factors such as smoking, infections, genetics, and environmental exposures contribute to their development. Diagnosis involves medical history, imaging, and pulmonary function tests. Management includes medications, lifestyle adjustments, and, in severe cases, surgical interventions. Early detection and comprehensive care are vital to mitigate symptoms, improve quality of life, and address the global health impact of pulmonary diseases.

• Tuberculosis (TB)
• Pulmonary Hypertension
• Interstitial Lung Diseases
• Bronchiectasis

Asthma is a severe chronic condition that affects the air ways. It involves inflammation that makes it difficult to breath inside the lungs. Asthma symptoms occur when the filling of the airways swell and therefore the muscles around them tighten. Mucus then fills the airways further reducing the amount of air produce an asthma “attack,” the coughing and tightness in your chest region that’s typical of asthma.

There are Airflow obstruction, Bronchospasm, Nocturnal Asthma, Chronic Obstructive Airways Disease, Asthma diagnosis & Treatment

Allergy develops when a person’s body becomes sensitized to a specific essence or condition in which the immune system reacts abnormally to certain foreign essence. Atopy is the genetic bias to develop the allergic diseases. When atopic people are exposed to allergens they can improves an immune reaction that may leads to allergic inflammation.

There are Food Allergy, Skin Allergy, Dust Allergy, Drug Allergy

Chronic Obstructive Pulmonary Disease (COPD) is a progressive lung disease characterized by airflow limitation and breathing difficulties, primarily caused by long-term exposure to irritants such as tobacco smoke. Ensuring optimal lung health from the neonatal stage is crucial in preventing long-term respiratory issues and improving overall quality of life. Neonatal care plays a vital role in shaping lung health, influencing the risk of developing COPD and other respiratory conditions later in life.

Neonatal Lung Development

Fetal lung development progresses through several stages, influenced by genetics and maternal health. Environmental exposures, such as maternal smoking, can adversely affect fetal lung growth.

Neonatal Risk Factors for COPD

Risk factors for impaired neonatal lung development include maternal smoking, premature birth, neonatal infections, and low birth weight.

4. Preventive Measures in Neonatal Care

Preventive measures include maternal health interventions, managing preterm labor with corticosteroids, surfactant therapy for premature infants, and infection prevention strategies.

5. Neonatal Respiratory Support

Respiratory support in NICUs includes mechanical ventilation, CPAP, high-frequency oscillatory ventilation, surfactant therapy, and oxygen therapy.

6. Long-term Impact of Neonatal Respiratory Care

Monitoring lung function from infancy through adulthood, early interventions, and regular follow-ups help prevent chronic lung diseases.

7. Innovations and Research in Neonatal Care for Lung Health

Advances in respiratory support technologies, genetic research, and personalized medicine approaches improve neonatal respiratory outcomes.

8. Multidisciplinary Approach to Neonatal Lung Health

A multidisciplinary approach involving obstetricians, neonatologists, pediatric pulmonologists, and respiratory therapists is essential. Family education and support are also vital.

9. Case Studies and Clinical Examples

Case studies highlight successful interventions and long-term outcomes in individuals who received comprehensive neonatal care.

10. Conclusion

Neonatal care is key in preventing COPD and promoting lung health. Addressing risk factors, providing effective respiratory support, and employing a multidisciplinary approach improve respiratory outcomes for neonates